Authorities have issued a fresh safety appeal to drivers amid another 24 hours of carnage on WA roads.

The state’s premier and police commissioner used separate media appearance to call for care behind the wheel, after the worlds of five families were shattered in the space of a day.

WATCH THE VIDEO ABOVE: Five people killed on WA roads in less than 24 hours.

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WA’s road toll stands at 112 deaths in 2025, the highest in a decade and 17 more than at the same time in 2024, a devastating 12-month period which itself triggered legislative change.

The latest life lost was a 65-year-old man killed when a Toyota Corolla hatchback travelling west on Great Eastern Hwy in Irishtown, 1.5 hours northeast of Perth, collided with a truck heading in the opposite direction just before 9am on Wednesday.

The Corolla driver was the sole occupant of his car.

The road train driver, a 47-year-old man, suffered minor injuries.

A 4km stretch of Great Eastern Hwy between Northam-Toodyay Rd and Northam Pithara Rd remains closed.

A driver has been killed in a crash with a truck in Irishtown, northeast of Perth. Credit: 7NEWS

The Toyota Corolla hatchback collided with a truck heading in the opposite direction. Credit: 7NEWS

On Tuesday morning, an e-scooter rider died after a collision with a truck in the southern Perth suburb of Bibra Lake.

The 35-year-old rider was injured about 10.40am and taken to Fiona Stanley Hospital in a critical condition but his injuries were too severe and he could not be saved.

Little more than an hour later, a Holden Colorado driver died from injuries suffered in a crash at an intersection in the Wheatbelt region of Petrudor.

The 65-year-old was flown 200km to Royal Perth Hospital after his car collided with a Kenworth truck towing two trailers just after 12pm.

He could not be saved and died from his injuries.

The truck driver, 25, suffered minor injuries and was taken to Dalwallinu District Hospital for treatment.

Later, a 45-year-old man died, and a 26-year-old man was injured, when their cars crashed on Broomehill-Gnowangerup Rd near Gnowangerup, six hours southeast of Perth, just after 4.30pm on Tuesday.

The surviving driver was airlifted to Royal Perth Hospital with serious injuries.

A 37-year-old pedestrian walking on Forrest Hwy was struck by a Nissan X-Trail in the South West coastal town of Binningup about 7pm on Tuesday.

The man died at the scene. The driver, a 49-year-old man, was uninjured.

Col Blanch said he is frustrated by WA’s road toll. Credit: 7NEWS

‘It just unacceptable’

WA Police Commissioner Col Blanch said he was “frustrated and angry” by the soaring death toll.

“It’s not just about the deceased. It’s about their families, it’s about the first responders, it’s about the witnesses to those accidents,” he said.

“Road deaths have so much consequential damage to people. It’s outrageous because most of them are preventable deaths.”

Speaking generally on road safety, he said police had impounded 1000 more cars this year than last, carried out more than 2.4 million breath tests, and dished out more enforcement fines “than ever before”.

But he said the message about not picking up your phone was not getting through.

“Looking outside your windscreen is the priority of driving,” he said.

“Having road awareness, situational awareness and safety awareness far exceeds anything that’s going on inside your vehicle.

“Turn things off, don’t look at it, just focus on driving.

“We’ve just got far too many deaths, families in total grief, it’s just unacceptable.”

The commissioner said the number of officers in the major crash division is under review.

“They’re managing the workload but as we’ve seen in the last two weeks, I’ll probably have to reassess that again,” he said.

WA Premier Roger Cook said the Bibra Lake tragedy is “another reminder that we need to look after each other on the roads”.

“I welcome the parliamentary inquiry into our e-scooter safety regime, regulations and opportunities but also we continue to look at what we can do in the long term to reduce deaths on our roads,” he said.