A car towing a caravan has plunged into a creek with two people now fighting for life.

At least two vehicles were involved in the crash on the Bruce Hwy near Roys Rd on Queensland’s Sunshine Coast on Thursday.

Queensland Ambulance Service said one patient, aged in their 60s, suffered life-threatening injuries to the chest and abdomen.

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They were rushed to Sunshine Coast University Hospital in a critical condition.

Another person was also treated at the scene for life-threatening injuries.

A third person was assessed but did not require treatment, QAS said.

One person was rushed to hospital in a critical condition from the crash near Roys Rd. Credit: 7NEWS

the crash happened on the Bruce Hwy. Credit: 7NEWS

Members of the public were seen performing CPR before paramedics arrived, with multiple emergency crews responding.

The exact number of vehicles involved and the cause of the crash are still under investigation.