Two men have been charged over a shocking high-speed collision that almost killed a family.

A Black MG SUV was captured on camera hurtling down Kings St, Newtown in Sydney’s inner west, at about 7pm on Sunday.

WATCH THE VIDEO ABOVE: A family is lucky to be alive after a high-speed head-on collision in Sydney

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The car was driving on the wrong side of the road when it clipped a silver Toyota Corolla before colliding head-on with a Mercedes SUV.

The 43-year-old male driver of the Mercedes and his passengers – a 67-year-old woman, 42-year-old woman, nine-year-old girl and 12-year-old boy – miraculously walked away from the crash.

They were all taken to Royal Prince Alfred Hospital with minor injuries.

The car was driving speeding down the wrong side of the road just prior to the crash. Credit: 7NEWS

The car hurtled into a Mercedes SUV, colliding head-on with the vehicle. Credit: 7NEWS

The Corolla driver, a 26-year-old woman, and two other drivers of vehicles caught up in the crash, another 26-year-old woman and a 65-year-old man, were not injured.

Kings St business owner Mohamed Zahour said the crash sounded like a bomb going off.

“When we came out we found like four to five cars had crashed,” he told 7NEWS.

“(The driver) thought he was on a highway.”

The MG driver, a 28-year-old man, was treated by paramedics before he was taken to St Vincent’s Hospital for mandatory testing.

He was later charged with drive in a manner dangerous and had his licence suspended.

The man was issued a court attendance notice to appear at Newtown Local Court in August.

Five cars were involved in the crash. Credit: 7NEWS

His passenger, a 20-year-old man, was arrested at the scene after he allegedly attempted to interfere in the police investigation and assaulted a female police officer and paramedics.

The man was taken to Royal Prince Alfred Hospital where he allegedly assaulted a male police officer and security staff while under police guard.

On Monday, he was released from the hospital and taken to a police station where he was charged with three offences relating to the assaults and investigation interference.

He was refused bail to appear at Parramatta Local Court on Tuesday.