A late night brawl has resulted in two brothers being shot multiple times.

Police were told about 15 people were reported to be involved in the fight on Boundary Rd in Chester Hill, western Sydney, about 10.30pm on Thursday.

WATCH THE VIDEO ABOVE: Two brothers shot in Chester Hill brawl

Know the news with the 7NEWS app: Download today

Arriving officers were unable to locate the group but did spot a black Audi being “driven in a dangerous manner”.

The car was stopped by police while reportedly taking two brothers, aged 24 and 27, to Westmead Hospital having suffered multiple gunshot wounds.

They were treated by paramedics before being taken to hospital in stable conditions.

The driver of the Audi spoke to police and was allowed to leave, pending further inquiries.

Two brothers have been shot during a late-night brawl in Chester Hill. Credit: 7NEWS

Investigators are now working to determine what sparked the brawl and why it escalated to gunfire.

Anyone with information has been urged to contact Crime Stoppers.