There are serious concerns for the welfare of a young girl who was last seen leaving a home two days ago.

Lyndel Ningella left a residence in Butler, in Perth’s north, about 5.45pm on Saturday.

It is believed she may have travelled as far as 80km to Kwinana, Leda, Parmelia or Wellard, suburbs that are about 30 minutes south of Perth’s CBD.

Know the news with the 7NEWS app: Download today

“WA Police are seeking public assistance to locate 10-year-old Lyndel ... for whom they hold welfare concerns,” authorities said, sharing a photo of the young girl with a beaming smile.

She was last seen wearing a black jumper and black shorts.

Lyndel is 160cm tall with a medium build, long brown hair with blonde ends, and brown eyes.

Anyone with information about her whereabouts should contact police immediately.

The appeal for information comes amid a high-profile search for teen hiker Lily Hooper, who vanished on Wednesday.