A man has died after his car was sent crashing into a tree in a collision in Sydney’s northwest.

The man, believed to be in his 60s, was driving a Subaru Outback when it collided with a Toyota Hilux on Lane Cove Rd in Ryde about 3pm on Thursday.

The impact sent the Subaru into a tree.

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The driver was treated before being rushed to hospital in a critical condition.

He later died.

The man is yet to be formally identified. 

The 34-year-old man driving the Hilux was also treated at the scene.

A crime scene was established and an investigation into the circumstances surrounding the crash is underway.

Anyone with information or relevant dashcam footage is urged to contact Crime Stoppers.